IJAIR NAAS Score : 3.99 ,ISSN : 2319-1473

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"Submissions Open For Vol. 14,Issue 6, May - June, 2026"


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IJAIR NAAS Score : 3.99 (2016 - 2020)
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IJAIR NAAS Score : 3.99 (2016 - 2020)
"Submissions Open For Vol. 14,Issue 6, May - June, 2026"


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IJAIR NAAS Score : 3.99 (2016 - 2020)
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IJECCE , IJEIR , IJAIR,
IJAIM , IJRAS , IJISM ,
IJIRES , IJASM , IJRIES,IJAHVS
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IJAIR NAAS Score : 3.99 (2016 - 2020)
"Submissions Open For Vol. 14,Issue 6, May - June, 2026"


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IJAIR NAAS Score : 3.99 (2016 - 2020)
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Synergistic Effect of Phosphorus and Nitrogen on Growth, Lipid Accumulation and Docosahexaenoic Acid Production in Crypthecodinium Cohnii

Waseem Safdar; Xinyi Zan; Yuanda Song
Docosahexaenoic acid (DHA) has numerous health benefits and widely used as an important component of infant formulae due to its prominent role in fetal brain and retina development. In this study, the synergetic effects of phosphate and nitrate concentrations on growth, lipid especially DHA biosynthesis and cell biochemical composition have been investigated in Crypthecodinium cohnii. The highest biomass was attained at synergy of high nitrogen (N) and phosphate (P, 23.5 ± 3.7g/L). When P concentration was increased from 0.1 g/L to 0.5 g/L with HN supplementation, biomass also increase by approx. 22%, however, at 2.0 g/L of P biomass decreased by 20 % which was unpredictable. Though, at higher P concentration, glucose dissimilation rate was higher (620 mg/L.h) as compared to at lower P concentration (330 mg/L.h). On the other hand, maximum TFA (36 % DCW) were produced at low P (0.1 g/L) concentration which was 35-40 % higher than that of high P (2.0 g/L) concentration. The maximum DHA content (3.3 g/L) and DHA productivity (0.54 g/L.d) was also obtained with 0.1 g/L KH2PO4. In this study, no significant effect was observed on lipid accumulation under LN or HN supply. It indicated that nitrogen limitation is not a trigger for lipid accumulation in C. cohnii. Therefore, a comprehensive study is required to evaluate this different mechanism of lipid accumulation.
Select Volume / Issue:
Year:
2017
Type of Publication:
Article
Keywords:
Crypthecodinium Cohnii; Docosahexaenoic Acid; DHA; LC-Pufas; Nitrogen Limitation; Phosphate; Lipid Accumulation
Journal:
IJAIR
Volume:
5
Number:
5
Pages:
768-775
Month:
March
ISSN:
2319-1473
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